Running Multiple Instances

How safe is it to run multiple instances of UpdateGenerator.exe? (From different folders, of course.) Are the variables and temp folders local or global?
I have separate copies for Windows, Windows Vista, and Office updates. At the moment I run downloads on them sequentially. It would be nice to run all of them at the same time.
I have separate copies for Windows, Windows Vista, and Office updates. At the moment I run downloads on them sequentially. It would be nice to run all of them at the same time.